VivoTrack 680 NIR Fluorescent Imaging Agent
VivoTrack 680 is a water soluble NIR (near infrared) fluorescent cell labeling agent that can label a variety of cell types. As cell migration is critical for many important in vivo biological functions, this labeling approach has the potential to provide a useful tool for research in inflammation, immunology and stem cells. VivoTrack 680 can label cells brightly and uniformly without requiring harsh organics such as DMSO or ethanol, chemicals known to affect cell function. The labeled cells retain excellent viability and normal proliferative capacity, and significant signal is retained in dividing cells in vitro for more than 7 days. Many different cell types can be labeled for in vivo transfer or implantation, and in vivo utility is illustrated by non-invasively tracking fluorescent primary macrophages to sites of inflammation by NIR fluorescent imaging.