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EDANS 【EDANS sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt]

EDANS, acid and its sodium salt are the most popular donors for developing FRET-based nucleic acid probes that is widely used in real time PCR assays. In addition, it is also used for developing protease substrates. EDANS, sodium salt is often paired with DABCYL or DABSYL in FRET-based probes. Its fluorescence is environment-sensitive.
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EDANS, sodium salt [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid, sodium salt]

 

Cat#

Size

Price

MW

Abs

Em

Soluble in

Storage 

615

1 g

$195

288.30

335 nm

493 nm

DMSO

4 oC and desiccated

 

Features and Biological Applications

EDANS, sodium salt is one of the most popular donors for developing FRET-based nucleic acid probes that is widely used in real time PCR assays. In addition, it is also used for developing protease substrates. EDANS, sodium salt is often paired with DABCYL or DABSYL in FRET-based probes. Its fluorescence is environment-sensitive.

 

 

References

1.  Chen, S., et al., Enzymatic activity characterization of sars coronavirus 3c-like protease by fluorescence resonance energy transfer technique.Acta Pharmacol Sin2005, 26, 99-106.

2.  Engfeldt, T., et al., Chemical synthesis of triple-labelled three-helix bundle binding proteins for specific fluorescent detection of unlabelled protein.Chembiochem2005, 6, 1043-1050.

3.  Zou, J., et al., Adam33 enzyme properties and substrate specificity.Biochemistry2005, 44, 4247-56.

 

 

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产品参数

Name EDANS
CAT# 615-1g CAS# 100900-07-0
Storage# 4°C Sealed & desiccated & Minimized light exposure Shelf Life# 24 months
Ex(nm)# 335 Em(nm)# 493
MW# 288.30 Solvent# DMSO

 

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